Study of SPG302 in Adults With Schizophrenia

Inclusion Criteria:

• Age 18-65

• Primary diagnosis of schizophrenia

• Clinical laboratory values within normal range or < 1.5 times ULN

• Currently prescribed only one antipsychotic medication, with stable dose for atleast 4 weeks

• Able and willing to provide written informed consent

Exclusion Criteria:

• Any physical or psychological condition that prohibits study completion

• Known cardiac disease

• Active or history of malignancy in the past 5 years

• History of clinically significant CNS event or diagnosis in the past 5 years.

• Receipt of investigational products within 30 days

• Blood donation within 30 days