Theory-based Social Media Intervention for Non-medical Use of Prescription Opioids in Young Adults

Phase

N/A

Condition

Opioid Use Disorder

Stimulant Use Disorder

Treatment

Theory-based and peer-led intervention on Instagram

Clinical Study ID

NCT06469749

Pro00135306

1K01DA058768-01A1

Ages 18-25
All Genders
Accepts Healthy Volunteers

Study Summary

Brief Summary

The purposes of this study are to develop and implement a peer-led intervention program on Instagram for promoting prescription opioid use management and fostering psychosocial skills among young adults who engage in non-medical use of prescription opioids in the United State. The specific aims of the study include:

(1) To implement and test the feasibility of the 12-week peer-led intervention modules on Instagram among young adults who are randomly assigned to either receive the intervention (intervention group) or not receive the intervention (control group)

Participants who are assigned to the intervention group will be paired with a peer leader and attend to peer-guided interactive modules on Instagram over 12 weeks. They will complete an online survey at 1st week and 12th week, as well as brief evening surveys every two days during the intervention. The control group will not take part in intervention activities but will complete an online survey at 1st week and 12th week.

Eligibility Criteria

Inclusion

Inclusion Criteria:

aged 18-25 years
from the U.S.
can read and speak English
engage in non-medical use of prescription opioids in the past three months: takingprescription opioids without a doctor's prescription/taking more doses ofprescription opioids than what a prescription allows/using prescription opioid forreasons other than a medical purpose
use Instagram three times a week or more in the past three months

Exclusion

Exclusion Criteria:

receiving substance use interventions in the past three months
are diagnosed with substance use disorders
are not proficient in English

Study Design

Theory-based and peer-led intervention on Instagram

November 01, 2026

March 31, 2029

Study Description

Non-medical use of prescription opioids (NMUPO) is a timely and significant public health issue in the United States (US). Young adults are the key population vulnerable to NMUPO. Existing literature indicates that NMUPO in young adults is influenced by a robust array of psychosocial factors. Tailored interventions guided by a psychosocial theory, such as the information-motivation-behavioral skills (IMB) model, are urgently needed for addressing NMUPO in young adults. One innovative approach is to reach out to and deliver psychosocial interventions to young adults via social media technology, yet limited efforts have sought to develop such interventions for NMUPO among young adults. Thus the scientific objective of this study is to develop a peer-led social media intervention designed to reduce NMUPO among young adults. The objective of this study is to obtain intensive mentored training essential to improving the theoretical and practical expertise needed to develop innovative and implementable peer-led psychosocial interventions for NMUPO in high-risk populations. This study aims to develop a theory-based social media intervention and evaluate the feasibility, acceptability, usability, and preliminary efficacy on NMUPO reduction and psychosocial changes of the intervention through a 12-week pilot randomized controlled trial among 70 NMUPO engaging young adults (35 for intervention and 35 for control) via pre-test, 12-week ecological momentary assessment (during the intervention), and post-tests (12-month follow-ups). The intervention development will be informed by formative findings on psychosocial aspects of NMUPO in young adults. This project will contribute to future largescale and fully-powered psychosocial interventions for NMUPO among young adults or other high-risk populations using innovative technology that can address challenges in traditional substance use interventions.

Connect with a study center

University of South Carolina
Columbia, South Carolina 29208
United States
Site Not Available
University of South Carolina
Columbia 4575352, South Carolina 4597040 29208
United States
Site Not Available

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