Autonomic Nervous System and Meridian Energy in Patients With Schizophrenia

Last updated: September 30, 2024
Sponsor: National Taiwan University Hospital
Overall Status: Active - Recruiting

Phase

N/A

Condition

Tourette's Syndrome

Psychosis

Mood Disorders

Treatment

no intervention

Clinical Study ID

NCT06617104
202407147RINC
  • Ages 18-65
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

This study aims to explore the differences in autonomic nervous function and meridian energy between schizophrenia patients and healthy individuals. By understanding the meridian and organ conditions of individuals, the study aims to align with the traditional Chinese medicine (TCM) concept of "treating disease before it arises" and provide comprehensive care to patients, thereby improving the quality of care.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Disease group:
  • Diagnosed with schizophrenia by a physician (ICD-10 code F20, such as F20.0,F20.1, F20.2, F20.3, F20.5, F20.89, or F20.9), with stable condition, and hasnot had any changes in medication dosage or admission to a psychiatric acutecare unit in the past 3 months.

  • Aged between 18 and 65 years.

  • Able to understand, speak, read, and write Mandarin or Taiwanese.

  1. Control group:
  • No history of chronic illness and no acute symptoms within the past month.

  • Aged between 18 and 65 years.

  • Able to understand, speak, read, and write Mandarin or Taiwanese.

Exclusion

Exclusion Criteria:

  1. Disease group:
  • Individuals with cardiovascular conditions, severe neurological disorders (e.g., organic brain disorders, early-stage dementia or diagnosed dementia), orsubstance abuse issues.

  • Individuals who have used medications affecting the autonomic nervous systemwithin the past month, such as mood stabilizers, antidepressants,angiotensin-converting enzyme inhibitors inhibitors, β-blockers, orantiarrhythmics.

  • Individuals with metallic implants that could affect heart rate variability.

  • Individuals with involuntary and uncontrollable body tremors.

  • Women currently menstruating.

  • Pregnant women.

  1. Control group:
  • Individuals with cardiovascular conditions, severe neurological disorders (e.g., organic brain disorders, early-stage dementia or diagnosed dementia), orsubstance abuse issues.

  • Individuals who have used medications affecting the autonomic nervous systemwithin the past month, such as psychiatric medications, angiotensin-convertingenzyme inhibitors inhibitors, β-blockers, or antiarrhythmics .

  • Individuals with metallic implants that could affect heart rate variability.

  • Individuals with involuntary and uncontrollable body tremors.

  • Women currently menstruating.

  • Pregnant women.

Study Design

Total Participants: 100
Treatment Group(s): 1
Primary Treatment: no intervention
Phase:
Study Start date:
September 05, 2024
Estimated Completion Date:
August 19, 2025

Study Description

Data collection was conducted at a medical center in northern Taiwan. Sample size estimation was performed using G*Power 3.1. A total of 50 patients with schizophrenia were assigned to the disease group, and 50 healthy individuals were assigned to the control group, with a total of 100 participants expected. Data collection included: personal demographic questionnaire, body constitution questionnaire (BCQ), WHOQOL-BREF (Taiwan version) for quality of life, brief psychiatric rating scale (BPRS), heart rate variability (HRV), meridian energy

Connect with a study center

  • National Taiwan University Hospital

    Taipei, 100229
    Taiwan

    Active - Recruiting

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