Cognitive Status, Fatigue and Inflammation in Patients With Immune Thrombocytopenia (ITP)

Inclusion Criteria:

• Patient diagnosed with chronic (ITP with > 1 year duration) primary ITP living inthe USA or the UK:

• On ITP pharmacologic treatment, regardless of last platelet count (below or above 100 x 10^9 counts/L);

• Patients in remission as per their most recent blood test (platelet count >100 x 10^9 counts/L) and without ITP-specific treatment for less than 1 year

• Adult patient who are 18 years or older at index date

• Patient who has received at least one initial first line therapy (corticosteroids [CS]/ intravenous immunoglobulin [IVIg]/ANTI d) with initial response (plateletcount ≥ 50 x 10^9 counts/L) as of index date

Exclusion Criteria:

• Secondary ITP

• Patients in remission as per their most recent blood test (platelet count >100 x 10^9 counts/L) and without ITP-specific treatment for 1 year or more

• Patients with recent or active infection recorded 14 days or less before index date;patients with uncontrolled chronic infections or who were recently diagnosed with achronic infection (≤14 days of index date).

• Patients with vaccination in 28 days before index date

• Patients treated with rilzabrutinib on or before index date