Biometrical Evaluation of the Efficacy of a Food Supplement Versus Placebo

Inclusion Criteria:

• Phototype: I to IV;

• Subjects with normal to dry skin;

• Subjects with healthy skin on the study area;

• Non-smokers;

• Has normal nutritional habits (not vegetarian/vegan);

• Is not pregnant or lactating;

• Has a BMI of 18 - 33 kg/m2;

• Is willing to refrain from taking dietary supplements (at best not at all, in anycase not during the last month before study start);

• Willing not to use any oral products or any nutritional supplementation aiming atimproving skin status during the course of the study;

• No history of malabsorption diseases, liver diseases, or diseases of the lipidmetabolism;

• Uses no medication, which may interact with the study product

Exclusion Criteria:

• For women: pregnant or nursing woman or woman planning to get pregnant during thestudy;

• Cutaneous pathology on the study zone (eczema, etc.);

• Subject with make-up on the day of the visit at the laboratory;

• Use of topical or systemic treatment during the previous weeks liable to interferewith the assessment of the efficacy of the study product:

• change in anti-wrinkle, smoothing and/or firming topical products withinprevious week on the studied zones,

• non-invasive procedures within previous month on the studied zones,

• intake of food supplement acting on skin within the three previous months,

• invasive procedures:

• deep chemical peeling within previous 3 months on the studied zones,

• mesotherapy, dermapen, laser within previous 6 months on the studiedzones,

• botox and/or hyaluronic acid injections within previous 12 months on thestudied zones;

• Intake of vitamin substances and diets comprising a change of normal eating habits;

• Known allergy to one or several investigational product´s ingredients;

• Participation in a nutritional study within the last 30 days;

• Surgical or internal diseases e.g. a metabolic or endocrine disease that may affectthe outcome of the study (e.g. diabetes, liver diseases, kidney disorders) or havinga history of medical or surgical events that may significantly affect the studyoutcome including any cardiovascular disease, skin disease, hypertension (>140/90 mmHg in three repeated measurements).