DCE-MRI Based on 4D Free Breathing for Predicting Preoperative Neoadjuvant Chemoradiotherapy for Esophageal Cancer

Last updated: December 24, 2024
Sponsor: Yunnan Cancer Hospital
Overall Status: Active - Recruiting

Phase

N/A

Condition

Esophageal Disorders

Esophageal Cancer

Digestive System Neoplasms

Treatment

The application value of MRI 4D Free Breathing DCE-MRI in the treatment of esophageal cancer

Clinical Study ID

NCT06755866
KYLX2024-273
  • Ages 18-80
  • All Genders

Study Summary

To prospectively collect medical images and clinical data related to esophageal cancer using 4D Free Breathing DCE-MRI technology, to evaluate the image quality in the diagnosis of esophageal cancer, and to predict the efficacy of preoperative neoadjuvant chemoradiotherapy for esophageal cancer.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Be 18 years of age and older;

  2. First diagnosis of esophageal squamous cell carcinoma confirmed by histopathologicalbiopsy;

  3. The clinical stage is cT1bcT2N+; or the clinical stage is cT3cT4 any N, (thoracicesophageal cancer, esophagogastric junction cancer);

  4. There are no contraindications to MRI examination

Exclusion

Exclusion Criteria:

  1. Have other primary tumors;

  2. The image quality does not meet the diagnostic criteria;

  3. Those who do not cooperate with the inspection;

  4. Patients who have received prior chemoradiotherapy

Study Design

Total Participants: 135
Treatment Group(s): 1
Primary Treatment: The application value of MRI 4D Free Breathing DCE-MRI in the treatment of esophageal cancer
Phase:
Study Start date:
November 26, 2024
Estimated Completion Date:
July 31, 2026

Connect with a study center

  • Yunnan Cancer Hospital

    Kunming City, Yunnan
    China

    Active - Recruiting

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