1 Florida Alzheimer’s Disease Research Center (1FL ADRC)

Last updated: February 2, 2023
Sponsor: National Institute on Aging (NIA) P30AG066506
Overall Status: Active - Recruiting

Phase

N/A

Condition

Alzheimer's Disease

Dementia

Treatment

N/A

Clinical Study ID

TX310343
20200763
  • Ages 65-95
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

This study aims to work with Researchers throughout the state of Florida to study the aging brain and learn more about how to detect and treat brain changes that affect memory during aging. Your participation will help increase the overall knowledge of Alzheimer’s disease and related dementias, and it will bring researchers one step closer to finding effective cures for Alzheimer’s disease.

Eligibility Criteria

Inclusion

Inclusion Criteria: At recruitment, participants will:

  • be between the ages of 65 and 95 years
  • have a minimum 6th-grade reading comprehension level
  • use English or Spanish as their primary language
  • have an available study partner (also called a “co-participant;”
  • agree that data can be included in NACC’s UDS and data and specimens can also be shared with other qualified scientists and repositories (e.g., NCRAD; Alzheimer’s Disease Neuroimaging Initiative; ADNI) (this is required by the ADRC funding);

Exclusion

Exclusion Criteria:

  • Individuals will be excluded if they have significant sensory (visual and hearing) deficits or major medical or psychiatric illnesses which would limit participation in longitudinal studies.

Study Design

Study Start date:
February 02, 2023
Estimated Completion Date:
January 02, 2024

Study Description

Consenting participants have a baseline visit and then are followed longitudinally until death or loss to follow-up. Follow-up visits occur approximately annually. Participants receive measures that are part of the NACC Uniform Data Set (UDS), as required of all ADRCs. We will also collect cognitive measures unique to our diverse cohort. Participants will also undergo a medical evaluation and a clinical interview by trained clinicians. Study partners will also be consented and interviewed. Participants have blood drawn for analysis. Local blood banking is performed through the neurodegeneration tissue bank. The total visit time is approximately 4-5 hours. Participants without contraindications (e.g. a pacemaker) will have an MRI on a different visit. Participants will undergo amyloid PET imaging unless there is a contraindication. Brain donation at the time of death is optional and is handled through Investigations of Neuropathologies Targeted by Clinical Trials in Alzheimer's Disease Patients.

Connect with a study center

  • University of Miami Center for Cognitive Neuroscience and Aging (CNSA)

    Miami, Florida 33136
    United States

    Active - Recruiting

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